此經在鹿野苑宣說，佛陀憶及自己最初在此宣說四聖諦，並囑咐比丘應追隨舍利弗與大目犍連，隨後舍利弗接續開示，詳加闡釋四聖諦；此段內容後被併入《大念處經》結語部分。

A discourse at Isipatana in which the Buddha recalls first teaching the Four Noble Truths there and exhorts the monks to follow Sāriputta and Mahā-Moggallāna, after which Sāriputta takes up the discourse to give a detailed exposition of the Truths — later incorporated into the Mahāsatipaṭṭhāna Sutta.